Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 6/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SLC5A1 | P13866 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1636787 | 0.83 | P2RX7 (0.46) | P2RX7SLC5A1L3MBTL1 | |
| SCHEMBL14827922 | 0.79 | P2RX7 (0.43) | P2RX7SLC5A1L3MBTL1ALDH1A1 | |
| SCHEMBL1637706 | 0.75 | P2RX7 (0.41) | P2RX7SLC5A1 | |
| SCHEMBL11195266 | 0.75 | P2RX7 (0.44) | P2RX7SLC5A1 | |
| SCHEMBL17741957 | 0.74 | — | — | |
| SCHEMBL14749789 | 0.74 | — | — | |
| SCHEMBL14629851 | 0.72 | — | — | |
| SCHEMBL10476562 | 0.72 | — | — | |
| SCHEMBL11191253 | 0.70 | SLC5A1 (0.34) | P2RX7SLC5A1 | |
| SCHEMBL11195883 | 0.69 | MMP2 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0085291-A1 | 2-Oxo-1-(aminocarbonylaminosulfonylaminocarbonyl)azetidines | E.R. Squibb & Sons, Inc. (US) | 1983-08-10 | — | — | EP | disclosed |