Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ACACA | Q13085 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11202515 | 0.98 | MEN1 (0.38) | PARP1TSHRALDH1A1KDM4ELMNA | |
| SCHEMBL11200250 | 0.97 | ALDH1A1 (0.37) | PARP1ALDH1A1KDM4ELMNANPSR1 | |
| SCHEMBL11199660 | 0.84 | MEN1 (0.51) | ALDH1A1KDM4ELMNANPSR1HIF1A | |
| SCHEMBL11204173 | 0.84 | HTR2C (0.47) | PARP1ALDH1A1KDM4ELMNANPSR1 | |
| SCHEMBL11199808 | 0.82 | HTR2C (0.50) | PARP1ALDH1A1KDM4ELMNANPSR1 | |
| SCHEMBL11201354 | 0.81 | HTR2C (0.49) | PARP1ALDH1A1KDM4ELMNANPSR1 | |
| SCHEMBL11197698 | 0.80 | ALDH1A1 (0.55) | TSHRALDH1A1KDM4ELMNANPSR1 | |
| SCHEMBL11203278 | 0.80 | KDM4E (0.30) | ALDH1A1KDM4ELMNAMEN1KMT2A | |
| SCHEMBL11203177 | 0.78 | RAB9A (0.45) | TSHRALDH1A1KDM4ELMNAPOLB | |
| SCHEMBL11207726 | 0.78 | HPGD (0.31) | ALDH1A1KDM4ENPSR1HTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0082023-A2 | Thienopyrimidine derivatives, their preparation and their medical use | SANKYO COMPANY LIMITED (JP) | 1983-06-22 | — | — | EP | disclosed |