Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.40 |
| ▸ | CDC42 | P60953 | 3/20 | 0.40 |
| ▸ | RAC1 | P63000 | 3/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.40 |
| ▸ | PAK1 | Q13153 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11206915 | 0.97 | PTGS2 (0.40) | PTGS2CDC42RAC1PTGS1PAK1 | |
| SCHEMBL11661754 | 0.94 | PTGS2 (0.47) | PTGS2CDC42RAC1PTGS1PAK1 | |
| SCHEMBL11201346 | 0.84 | PTGS2 (0.58) | PTGS2CDC42RAC1PTGS1PAK1 | |
| SCHEMBL11198815 | 0.84 | PTGS2 (0.45) | PTGS2CDC42RAC1PTGS1PAK1 | |
| SCHEMBL11198401 | 0.83 | MEN1 (0.39) | MEN1POLBKMT2AALDH1A1ADORA2B | |
| SCHEMBL11202198 | 0.83 | CDC42 (0.59) | PTGS2CDC42RAC1PTGS1PAK1 | |
| SCHEMBL11201403 | 0.83 | PTGS2 (0.44) | PTGS2CDC42RAC1PTGS1PAK1 | |
| SCHEMBL11197976 | 0.83 | PTGS2 (0.42) | PTGS2CDC42RAC1PTGS1PAK1 | |
| SCHEMBL11198264 | 0.83 | PTGS2 (0.44) | PTGS2CDC42RAC1PTGS1PAK1 | |
| SCHEMBL11203051 | 0.82 | PTGS2 (0.44) | PTGS2CDC42RAC1PTGS1PAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4410534-A | 3-Substituted-5,6,7,8-tetrahydropyrrolo[1,2-a]-pyridine-and 6,7,8,9-tetrahydro-5H-pyrrolo[1,2-a]-azepine carboxylic acid derivatives useful as blood platelet aggregation inhibitors | SYNTEX (U.S.A.) INC. (US) | 1983-10-18 | — | — | US | disclosed |