Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 2/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | ADK | P55263 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.33 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.33 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 2/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.33 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.32 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL81650 | 0.68 | NISCH (0.59) | NISCHMTORADKALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL1536214 | 0.66 | NISCH (0.56) | NISCHMTORADKALDH1A1KDM4E | |
| SCHEMBL28425230 | 0.66 | NISCH (0.56) | NISCHMTORADKALDH1A1KDM4E | |
| SCHEMBL9091369 | 0.64 | NPC1 (0.50) | NISCHALDH1A1KDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL7471726 | 0.64 | ADRA1A (0.48) | NISCHMTORADKALDH1A1KDM4E | |
| SCHEMBL2943926 | 0.64 | NISCH (0.44) | NISCHALDH1A1KDM4EKMT2ATYRO3 | |
| SCHEMBL1205638 | 0.63 | — | — | |
| SCHEMBL9855245 | 0.61 | NISCH (0.47) | NISCHALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7932131 | 0.61 | NISCH (0.46) | NISCHMTORADKALDH1A1KDM4E | |
| SCHEMBL4732940 | 0.60 | CSNK1A1 (0.42) | NISCHMTORADKALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0093589-A1 | Thiadiazolylimidazolidinones, intermediates, formulations and herbicidal method | ELI LILLY AND COMPANY (US) | 1983-11-09 | — | — | EP | disclosed |