Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 2/20 | 0.36 |
| ▸ | TNKS | O95271 | 1/20 | 0.36 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.35 |
| ▸ | GSK3A | P49840 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.35 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.35 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15043722 | 0.80 | HTR1D (0.51) | NISCHKMT2ARAB9ALMNANOTUM | |
| SCHEMBL2943926 | 0.80 | NISCH (0.44) | NISCHKMT2ARAB9AALDH1A1PARP1 | |
| SCHEMBL11787892 | 0.74 | RAB9A (0.42) | NISCHMEN1KMT2ARAB9ALMNA | |
| SCHEMBL30205262 | 0.72 | NPC1 (0.45) | NISCHKMT2ARAB9ALMNAALDH1A1 | |
| SCHEMBL9381489 | 0.71 | GABRA1 (0.39) | MEN1KMT2ARAB9ALMNAALDH1A1 | |
| SCHEMBL9855447 | 0.65 | NISCH (0.47) | NISCHMEN1KMT2ARAB9ALMNA | |
| SCHEMBL9091369 | 0.64 | NPC1 (0.50) | NISCHKMT2ARAB9ALMNAALDH1A1 | |
| SCHEMBL1886692 | 0.64 | NISCH (1.00) | NISCHLMNAMAOAMAOB | |
| SCHEMBL22434764 | 0.63 | NISCH (0.48) | NISCHMEN1KMT2ARAB9ALMNA | |
| SCHEMBL11201384 | 0.61 | NISCH (0.38) | NISCHMEN1KMT2AALDH1A1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0158000-B1 | REGIO AND OPTICAL ISOMERS OF IMIDAZOLINYL TOLUIC ACIDS, ESTERS AND SALTS, THEIR METHOD OF PREPARATION AND THEIR USE AS HERBICIDAL AGENTS | AMERICAN CYANAMID COMPANY (US) | 1991-06-19 | — | — | EP | disclosed |