Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.42 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.42 |
| ▸ | HTR1A | P08908 | 2/20 | 0.42 |
| ▸ | DRD4 | P21917 | 2/20 | 0.42 |
| ▸ | HTR2C | P28335 | 2/20 | 0.42 |
| ▸ | HTR2B | P41595 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | HTR5A | P47898 | 1/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11198743 | 0.89 | DRD2 (0.52) | SIGMAR1TMEM97HTR1ADRD4HTR2C | |
| SCHEMBL11200098 | 0.84 | KDM2B (0.46) | SIGMAR1TMEM97HTR1ADRD4HTR2C | |
| SCHEMBL3314947 | 0.84 | SIGMAR1 (0.61) | SIGMAR1TMEM97HTR1ADRD4HTR2C | |
| SCHEMBL11200175 | 0.84 | KDM4E (0.45) | SIGMAR1TMEM97HTR1ADRD4HTR2C | |
| SCHEMBL11194765 | 0.84 | CHRM5 (0.42) | CHRM5CHRM1CHRM2CHRM3 | |
| SCHEMBL11193322 | 0.82 | SIGMAR1 (0.56) | SIGMAR1TMEM97HTR1ADRD4HTR2C | |
| SCHEMBL11203775 | 0.80 | DRD3 (0.40) | DRD3DRD2 | |
| SCHEMBL11196336 | 0.80 | GRIN2B (0.50) | — | |
| SCHEMBL10638314 | 0.79 | CHRM2 (0.44) | CHRM5CHRM1CHRM2CHRM3 | |
| SCHEMBL8352095 | 0.78 | MEN1 (0.59) | SIGMAR1TMEM97HTR1ADRD4HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4382942-A | ANTIEMETICS, PARKINSON*S DISEASE | ROUSSEL UCLAF (FR) | 1983-05-10 | — | — | US | disclosed |