Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | HRH1 | P35367 | 9/20 | 0.47 |
| ▸ | DRD1 | P21728 | 5/20 | 0.47 |
| ▸ | DRD2 | P14416 | 4/20 | 0.47 |
| ▸ | DRD4 | P21917 | 4/20 | 0.47 |
| ▸ | DRD5 | P21918 | 4/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9162703 | 0.77 | MAOA (0.52) | MAOAMAOBHRH1DRD1DRD2 | |
| SCHEMBL4350509 | 0.77 | MAOA (0.52) | MAOAMAOBHRH1DRD1DRD2 | |
| SCHEMBL28729808 | 0.75 | MAOA (0.50) | MAOAMAOBHRH1DRD1DRD2 | |
| SCHEMBL10835682 | 0.75 | MAOA (0.57) | MAOAMAOBHRH1DRD1DRD2 | |
| SCHEMBL28512555 | 0.75 | DRD1 (0.48) | MAOAMAOBHRH1DRD1DRD2 | |
| SCHEMBL13050344 | 0.74 | HRH1 (0.57) | HRH1DRD1DRD2DRD4DRD5 | |
| SCHEMBL621779 | 0.74 | HTR1A (0.58) | HRH1DRD1DRD2DRD4DRD5 | |
| Hydrochloric Acid SCHEMBL8856997 | 0.73 | MAOA (0.56) | MAOAMAOBHRH1DRD1DRD2 | |
| SCHEMBL10983124 | 0.73 | KMT2A (0.58) | MAOAMAOBHRH1DRD1DRD2 | |
| SCHEMBL11204775 | 0.73 | KDM4E (0.45) | TP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4391828-A | Dibutylorthobenzylmethoxybenzenes and dibutylorthocinnamylmethoxybenzenes as mosquito larvae growth inhibitors | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1983-07-05 | — | — | US | disclosed |