Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 14/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 5/20 | 0.33 |
| ▸ | PREP | P48147 | 1/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 3/20 | 0.31 |
| ▸ | JAK1 | P23458 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11196676 | 0.89 | DPP4 (0.33) | DPP4DPP7PREPDPP8DPP9 | |
| SCHEMBL11193905 | 0.88 | GBA2 (0.33) | DPP4DPP7PREPDPP8DPP9 | |
| SCHEMBL11200959 | 0.83 | DPP4 (0.31) | DPP4DPP7PREP | |
| SCHEMBL11195793 | 0.83 | DPP4 (0.31) | DPP4DPP7PREP | |
| SCHEMBL11200586 | 0.81 | DPP4 (0.36) | DPP4PREPDPP8DPP9JAK2 | |
| SCHEMBL11197112 | 0.80 | ALDH1A1 (0.41) | DPP4PREPDPP8 | |
| SCHEMBL11201934 | 0.79 | GBA2 (0.51) | DPP4 | |
| SCHEMBL11197226 | 0.78 | HTT (0.36) | DPP4DPP7DPP8DPP9JAK2 | |
| SCHEMBL11196802 | 0.76 | DPP4 (0.34) | DPP4DPP7PREPDPP8DPP9 | |
| SCHEMBL11192495 | 0.75 | RAB9A (0.48) | DPP4PREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4376731-A | 2-NITRILES THEREOF | BOEHRINGER MANNHEIM GMBH (DE) | 1983-03-15 | — | — | US | disclosed |