Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | ASPH | Q12797 | 1/20 | 0.43 |
| ▸ | RIOX2 | Q8IUF8 | 1/20 | 0.43 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | UBE2I | P63279 | 1/20 | 0.42 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.42 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11202475 | 0.91 | SMN1; SMN2 (0.46) | LMNAMEN1KMT2ASMN1; SMN2CA2 | |
| SCHEMBL11202899 | 0.89 | CISD1 (0.42) | LMNAMEN1KMT2ASMN1; SMN2CA2 | |
| SCHEMBL11165688 | 0.89 | CISD1 (0.49) | LMNACA2CA12CA1CA9 | |
| SCHEMBL11170323 | 0.87 | CISD1 (0.51) | LMNAMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL11194787 | 0.84 | KDM4E (0.46) | LMNAMEN1KMT2ACA2KDM4E | |
| SCHEMBL11159696 | 0.83 | CISD1 (0.58) | LMNAMEN1KMT2ASMN1; SMN2CA2 | |
| SCHEMBL11167102 | 0.82 | KDM5A (0.43) | CA2CA12CA1CA9PPARA | |
| SCHEMBL11192732 | 0.79 | KDM4E (0.59) | LMNACA2CA12CA1KDM4E | |
| SCHEMBL11165513 | 0.79 | CISD1 (0.42) | LMNAMEN1KMT2ASMN1; SMN2CA2 | |
| SCHEMBL11167238 | 0.79 | ALDH1A1 (0.53) | LMNAMEN1KMT2ASMN1; SMN2CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4393072-A | Thienylbenzoic acid derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-07-12 | — | — | US | disclosed |