Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CISD1 | Q9NZ45 | 3/20 | 0.41 |
| ▸ | CDC7 | O00311 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | ACLY | P53396 | 1/20 | 0.39 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.38 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11170323 | 0.90 | CISD1 (0.51) | CISD1ACLYPPARAPOLBSCN9A | |
| SCHEMBL11165688 | 0.90 | CISD1 (0.49) | RAB9ACISD1POLBSCN9ACA12 | |
| SCHEMBL11202475 | 0.86 | SMN1; SMN2 (0.46) | TAS2R14POLBCA1CA2CA7 | |
| SCHEMBL11165742 | 0.85 | KDM5A (0.43) | KDM5AKDM4CKDM5BCISD1CDC7 | |
| SCHEMBL11202899 | 0.84 | CISD1 (0.42) | RAB9ACISD1POLBSCN9ACA12 | |
| SCHEMBL11159696 | 0.84 | CISD1 (0.58) | KDM4CRAB9ACISD1ACLYPOLB | |
| SCHEMBL11165513 | 0.83 | CISD1 (0.42) | MAPK1RAB9ACISD1ACLYPOLB | |
| SCHEMBL11201807 | 0.82 | LMNA (0.44) | RAB9ACISD1PPARAPOLBCA12 | |
| SCHEMBL11167238 | 0.80 | ALDH1A1 (0.53) | KDM4CRAB9ACISD1POLBCA12 | |
| SCHEMBL11192732 | 0.78 | KDM4E (0.59) | CISD1CA12CA1CA2CA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4393072-A | Thienylbenzoic acid derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-07-12 | — | — | US | disclosed |
| EP-0011282-B1 | THIENYLBENZOIC-ACID DERIVATIVES, PROCESS FOR THEIR PRODUCTION, AND PHARMACEUTICAL PREPARATIONS CONTAINING THESE COMPOUNDS | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-02-16 | — | — | EP | disclosed |
| EP-0011282-A1 | Thienylbenzoic-acid derivatives, process for their production, and pharmaceutical preparations containing these compounds | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-05-28 | — | — | EP | disclosed |