Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11208198 | 0.79 | ALDH1A1 (0.47) | LMNAPOLBMAPK1ALDH1A1HPGD | |
| SCHEMBL6405062 | 0.78 | HDAC3 (0.41) | LMNAPOLBMAPK1ALDH1A1HPGD | |
| SCHEMBL11208326 | 0.76 | CYP1A2 (0.44) | LMNAPOLBALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL11264686 | 0.73 | ALDH1A1 (0.42) | LMNAPOLBMAPK1ALDH1A1HPGD | |
| SCHEMBL10523948 | 0.73 | HSD17B10 (0.48) | POLBMAPK1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL6688633 | 0.72 | MAPT (0.43) | LMNAPOLBMAPK1ALDH1A1HPGD | |
| SCHEMBL11211696 | 0.72 | OPRM1 (0.42) | ALDH1A1HPGDMTNR1AMTNR1BSMN1; SMN2 | |
| SCHEMBL11204292 | 0.70 | ALDH1A1 (0.45) | POLBMAPK1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL11265491 | 0.69 | FFAR1 (0.38) | LMNAALDH1A1HPGDMTNR1AMTNR1B | |
| SCHEMBL11208113 | 0.69 | KCNN4 (0.44) | MAPK1ALDH1A1HPGDMTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0029719-B1 | VULCANIZABLE RUBBER COMPOSITIONS INHIBITED FROM PREMATURE VULCANIZATION BY METHYLENE THIOETHERS, AND NOVEL METHYLENE THIOETHERS | MONSANTO COMPANY (US) | 1983-02-16 | — | — | EP | disclosed |
| US-4342705-A | CONTAINING CARBONYL OR CYANO FUNCTIONAL GROUPS, USEFUL AS VULCANIZATION INHIBITORS | MONSANTO COMPANY (US) | 1982-08-03 | — | — | US | disclosed |
| EP-0029719-A1 | Vulcanizable rubber compositions inhibited from premature vulcanization by methylene thioethers, and novel methylene thioethers | MONSANTO COMPANY (US) | 1981-06-03 | — | — | EP | disclosed |
| US-4271050-A | Vulcanizable rubber compositions inhibited from premature vulcanization by methylene thioethers | MONSANTO COMPANY (US) | 1981-06-02 | — | — | US | disclosed |