Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.48 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16435341 | 0.86 | TSHR (0.58) | TSHRACHEMAPTALDH1A1TDP1 | |
| SCHEMBL11200693 | 0.77 | ALDH1A1 (0.52) | TSHRACHEMAPTALDH1A1TDP1 | |
| SCHEMBL11882150 | 0.77 | TDP1 (0.63) | TSHRMAPTALDH1A1TDP1LMNA | |
| SCHEMBL11889464 | 0.77 | TDP1 (0.63) | TSHRMAPTALDH1A1TDP1LMNA | |
| SCHEMBL6738366 | 0.76 | TSHR (0.76) | TSHRACHEMAPTALDH1A1TDP1 | |
| SCHEMBL5418627 | 0.76 | ALDH1A1 (0.58) | TSHRACHEMAPTALDH1A1TDP1 | |
| SCHEMBL10840844 | 0.75 | TSHR (0.61) | TSHRACHEMAPTALDH1A1TDP1 | |
| SCHEMBL7905747 | 0.75 | LMNA (0.55) | TSHRMAPTALDH1A1TDP1LMNA | |
| SCHEMBL11392461 | 0.74 | TSHR (0.73) | TSHRACHEMAPTALDH1A1TDP1 | |
| SCHEMBL11392466 | 0.74 | TSHR (0.73) | TSHRACHEMAPTALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0088938-A1 | Use of pyridine compounds for the manufacture of medicaments with an antihypoxemia and ischemia-protective activity | BAYER AG (DE) | 1983-09-21 | — | — | EP | disclosed |
| EP-0088940-A1 | Pyridine-carboxylic-acid esters, process for their preparation and their use as pharmaceutical compositions | BAYER AG (DE) | 1983-09-21 | — | — | EP | disclosed |