Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10337709 | 0.84 | TSHR (0.59) | APEX1HTTTSHRTP53 | |
| SCHEMBL7831567 | 0.81 | ALDH1A1 (0.56) | APEX1TSHRMEN1KMT2A | |
| SCHEMBL31223199 | 0.81 | IDO1 (0.65) | HTTTSHRMEN1KMT2ACA12 | |
| SCHEMBL9335 | 0.81 | IDO1 (0.65) | HTTTSHRMEN1KMT2ACA12 | |
| SCHEMBL11853769 | 0.80 | MEN1 (0.73) | APEX1HTTTSHRMEN1KMT2A | |
| SCHEMBL11195792 | 0.80 | APEX1 (0.73) | APEX1HTTTSHRTP53 | |
| SCHEMBL848037 | 0.80 | MAPT (0.60) | APEX1HTTMEN1KMT2ATP53 | |
| SCHEMBL2727648 | 0.79 | SMN1; SMN2 (0.49) | HTTMEN1KMT2ATP53IDO1 | |
| SCHEMBL1137180 | 0.79 | MAOB (0.51) | HTTMEN1KMT2AIDO1MAOB | |
| SCHEMBL3931647 | 0.78 | SMN1; SMN2 (0.50) | TSHRMEN1KMT2AIDO1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4410697-A | CARBAMATE, AMINE, TERTIARY AMINE CATALYST | REANAL FINOMVEGYSZERGYAR (HU) | 1983-10-18 | — | — | US | disclosed |
| US-3975418-A | 4-Bromo-3-chloro-phenylisocyanate | CIBA-GEIGY AG (CH) | 1976-08-17 | — | — | US | disclosed |