Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | APEX1 | P27695 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11195792 | 0.84 | APEX1 (0.73) | TSHRAPEX1HTTTP53 | |
| SCHEMBL11202141 | 0.84 | APEX1 (0.54) | TSHRAPEX1HTTTP53 | |
| SCHEMBL11502522 | 0.84 | APEX1 (0.73) | TSHRAPEX1HTTNPC1RAB9A | |
| SCHEMBL687878 | 0.80 | TSHR (0.79) | TSHRAPEX1 | |
| SCHEMBL30368269 | 0.79 | RAB9A (0.58) | TSHRHTTNPC1RAB9AHPGD | |
| SCHEMBL863069 | 0.79 | RAB9A (0.58) | TSHRHTTNPC1RAB9AHPGD | |
| SCHEMBL12292880 | 0.79 | TSHR (0.66) | TSHRAPEX1HTT | |
| SCHEMBL23169463 | 0.78 | RAB9A (0.48) | TSHRAPEX1HTTRAB9AHPGD | |
| SCHEMBL23169533 | 0.76 | TP53 (0.64) | TSHRAPEX1HTTNPC1RAB9A | |
| SCHEMBL19019393 | 0.76 | TP53 (0.69) | TSHRAPEX1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2000761-A | — | — | None | — | — | JP | disclosed |
| JP-H02761-A | DIFLUOROPHENYL UREA | BAYER AG | 1990-01-05 | — | — | JP | disclosed |