Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.50 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | MC4R | P32245 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | MC3R | P41968 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15012541 | 0.76 | TSHR (0.57) | MAPTKDM4ENAPRTHCAR2TSHR | |
| SCHEMBL11904045 | 0.76 | MAPT (0.63) | MAPTKDM4ETSHRLMNAADORA3 | |
| SCHEMBL4458878 | 0.75 | PKM (0.58) | NAPRTLMNAGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL12218526 | 0.75 | GAA (0.64) | MAPTTSHRLMNAGAASMN1; SMN2 | |
| SCHEMBL20451349 | 0.75 | GAA (0.64) | MAPTTSHRLMNAGAASMN1; SMN2 | |
| SCHEMBL3679578 | 0.75 | MAPT (0.69) | MAPTKDM4ENAPRTHCAR2TSHR | |
| SCHEMBL27965294 | 0.73 | KDM4E (0.44) | MAPTKDM4ENAPRTHCAR2TSHR | |
| SCHEMBL6449861 | 0.73 | CYP3A4 (0.58) | NAPRTLMNAADORA3GAASMN1; SMN2 | |
| SCHEMBL1451131 | 0.72 | MAPT (0.39) | MAPTLMNAGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL3679576 | 0.72 | MAPT (0.68) | MAPTKDM4ENAPRTHCAR2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0076085-A1 | Production of monoacylpyrazines | PHILIP MORRIS INCORPORATED (US) | 1983-04-06 | — | — | EP | disclosed |