Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | MC4R | P32245 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | MC3R | P41968 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11904184 | 0.77 | ALDH1A1 (0.54) | MAPTLMNASMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL11202151 | 0.76 | MAPT (0.63) | MAPTLMNAGAASMYD3SMN1; SMN2 | |
| SCHEMBL20451349 | 0.75 | GAA (0.64) | MAPTLMNAGAASMYD3SMN1; SMN2 | |
| SCHEMBL12218526 | 0.75 | GAA (0.64) | MAPTLMNAGAASMYD3SMN1; SMN2 | |
| SCHEMBL3679578 | 0.74 | MAPT (0.69) | MAPTLMNAGAASMN1; SMN2TSHR | |
| SCHEMBL3679576 | 0.72 | MAPT (0.68) | MAPTLMNAGAASMYD3SMN1; SMN2 | |
| SCHEMBL8234022 | 0.71 | LMNA (0.62) | MAPTLMNAGAASMYD3SMN1; SMN2 | |
| SCHEMBL27843558 | 0.71 | ADORA3 (0.55) | GAASMN1; SMN2TSHRKMT2AADORA3 | |
| SCHEMBL2411972 | 0.70 | MAPT (0.53) | MAPTLMNAGAASMYD3SMN1; SMN2 | |
| SCHEMBL10043293 | 0.70 | MAPT (0.53) | MAPTLMNAGAASMYD3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1975162-B1 | OXAZOLONE DERIVATIVE | SEIKAGAKU KOGYO CO LTD (JP) | 2012-08-15 | — | — | EP | disclosed |