Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.56 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 5/20 | 0.54 |
| ▸ | RAB9A | P51151 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
| ▸ | EGFR | P00533 | 1/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1129948 | 0.86 | KMT2A (0.77) | KMT2APKMALOX15KCNK3KCNK9 | |
| SCHEMBL6346820 | 0.84 | KMT2A (0.65) | KMT2APKMALOX15KCNK3KCNK9 | |
| SCHEMBL4247707 | 0.81 | NPC1 (0.68) | KMT2APKMKCNK3KCNK9NPC1 | |
| SCHEMBL4241801 | 0.81 | NPC1 (0.68) | KMT2APKMKCNK3KCNK9NPC1 | |
| SCHEMBL11793228 | 0.80 | KMT2A (0.73) | KMT2APKMALOX15KCNK3KCNK9 | |
| SCHEMBL11202607 | 0.80 | KMT2A (0.62) | KMT2APKMALOX15KCNK3KCNK9 | |
| SCHEMBL11204834 | 0.80 | POLB (0.54) | KMT2APKMNPC1RAB9AMEN1 | |
| SCHEMBL2831786 | 0.79 | NPC1 (0.72) | KMT2ANPC1RAB9AMEN1MAPT | |
| Hydrochloric Acid SCHEMBL11197738 | 0.78 | KMT2A (0.60) | KMT2APKMALOX15KCNK3KCNK9 | |
| SCHEMBL131786 | 0.78 | P2RX1 (0.74) | KMT2ANPC1RAB9AMEN1TMPRSS4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002060373-A2 | INDOLE DERIVATIVES AND THEIR USES AS HEPARANASE INHIBITORS | INSIGHT STRATEGY AND MARKETING LTD (IL) | 2002-08-08 | — | — | WO | disclosed |