Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.69 |
| ▸ | TSHR | P16473 | 1/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.69 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11200813 | 0.83 | ALDH1A1 (0.71) | ALDH1A1CYP1A2TSHRMAPK1HTT | |
| SCHEMBL5169135 | 0.80 | CYP1A2 (0.73) | ALDH1A1CYP1A2TSHRMAPK1HTT | |
| Hydrochloric Acid SCHEMBL11193596 | 0.79 | ALDH1A1 (0.71) | ALDH1A1CYP1A2TSHRMAPK1HTT | |
| SCHEMBL1032275 | 0.78 | SMN1; SMN2 (0.53) | ALDH1A1CYP1A2TSHRSMN1; SMN2POLB | |
| SCHEMBL11177073 | 0.77 | ALDH1A1 (0.55) | ALDH1A1CYP1A2TSHRMAPK1HTT | |
| SCHEMBL8305183 | 0.76 | ALDH1A1 (0.61) | ALDH1A1CYP1A2TSHRMAPK1HTT | |
| SCHEMBL11110574 | 0.76 | ALDH1A1 (0.54) | ALDH1A1CYP1A2TSHRMAPK1HTT | |
| SCHEMBL12851363 | 0.76 | HRH3 (0.56) | ALDH1A1CYP1A2MAPK1HTTSMN1; SMN2 | |
| SCHEMBL6130015 | 0.75 | CYP1A2 (0.63) | ALDH1A1CYP1A2TSHRMAPK1SMN1; SMN2 | |
| SCHEMBL8352671 | 0.75 | KMT2A (0.58) | ALDH1A1CYP1A2TSHRHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4379158-A | Antisecretory imidazole amidine compounds, composition and method of use | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1983-04-05 | — | — | US | disclosed |
| US-4252819-A | ANTISECRETORY AGENTS; GASTRIC JUICE | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1981-02-24 | — | — | US | disclosed |