Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | HRH1 | P35367 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | LIN28A | Q9H9Z2 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.47 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31058796 | 0.91 | ALDH1A1 (0.59) | CYP1A2ALDH1A1TSHRSMN1; SMN2NPC1 | |
| SCHEMBL2592282 | 0.89 | CYP1A2 (0.54) | CYP1A2ALDH1A1TSHRSMN1; SMN2NPC1 | |
| SCHEMBL30732408 | 0.89 | ALDH1A1 (0.58) | CYP1A2ALDH1A1TSHRSMN1; SMN2NPC1 | |
| SCHEMBL12055882 | 0.89 | ALDH1A1 (0.58) | CYP1A2ALDH1A1TSHRSMN1; SMN2NPC1 | |
| SCHEMBL11329150 | 0.87 | ALDH1A1 (0.61) | CYP1A2ALDH1A1TSHRSMN1; SMN2NPC1 | |
| SCHEMBL5797012 | 0.87 | CYP1A2 (0.56) | CYP1A2ALDH1A1TSHRSMN1; SMN2NPC1 | |
| SCHEMBL11445226 | 0.85 | SMN1; SMN2 (0.57) | CYP1A2ALDH1A1TSHRSMN1; SMN2NPC1 | |
| Ammonia Solution, Strong SCHEMBL10911999 | 0.85 | ALDH1A1 (0.59) | CYP1A2ALDH1A1TSHRSMN1; SMN2NPC1 | |
| SCHEMBL23132326 | 0.83 | ALDH1A1 (0.57) | CYP1A2ALDH1A1TSHRSMN1; SMN2NPC1 | |
| SCHEMBL19305939 | 0.83 | ALDH1A1 (0.57) | CYP1A2ALDH1A1TSHRSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109134354-A | The synthetic method of 2- picolyl thioether and the synthesis technology of related drugs | 天津科技大学 | 2019-01-04 | — | — | CN | claimed |
| JP-63201168-A | — | — | None | — | — | JP | disclosed |
| CN-115772119-B | Synthesis method of N-heterocyclic thioether compound | 信阳师范学院 | 2024-06-07 | — | — | CN | disclosed |
| CN-117924129-A | Preparation method of sulfone and sulfoxide compounds | 长江师范学院 | 2024-04-26 | — | — | CN | disclosed |
| CN-115772119-A | Synthetic method of N-heterocyclic thioether compound | 信阳师范学院 | 2023-03-10 | — | — | CN | disclosed |
| CN-111559976-B | Synthetic method of heteroaryl thioether | 扬州大学 | 2022-05-13 | — | — | CN | disclosed |
| CN-113636962-B | Method for preparing sulfoxide compound by catalyzing thioether compound oxidation through visible light excited aqueous solution quantum dots | 大连理工大学 | 2022-05-10 | — | — | CN | disclosed |
| CN-109134354-B | Synthesis method of 2-pyridylmethyl thioether and synthesis process of related drugs | 天津科技大学 | 2022-03-25 | — | — | CN | disclosed |
| CN-109134354-B | Synthesis method of 2-pyridylmethyl thioether and synthesis process of related drugs | 天津科技大学 | 2022-03-25 | — | — | CN | disclosed |
| CN-113636962-A | Method for preparing sulfoxide compound by catalyzing thioether compound oxidation through visible light excited aqueous solution quantum dots | 大连理工大学 | 2021-11-12 | — | — | CN | disclosed |
| WO-2000009498-A1 | PRODRUGS OF PROTON PUMP INHIBITORS | PARTNERSHIP OF MICHAEL E. GARST, GEORGE SACHS AND JAI MOO SHIN (US) | 2000-02-24 | — | — | WO | disclosed |
| EP-0857171-A2 | IMIDAZOLE DERIVATIVES AND THE USE THEREOF AS NITROGEN MONOXIDE SYNTHASE INHIBITORS | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-08-12 | — | — | EP | disclosed |
| WO-1997015555-A2 | IMIDAZOLE DERIVATIVES AND THE USE THEREOF AS NITROGEN MONOXIDE SYNTHASE INHIBITORS | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-05-01 | — | — | WO | disclosed |
| US-5475024-A | Useful in treating liver disease | EISAI CO., LTD. (JP) | 1995-12-12 | — | — | US | disclosed |
| US-5292901-A | Benzodioxole derivatives | EISAI CO., LTD. (JP) | 1994-03-08 | — | — | US | disclosed |
| EP-0281098-B1 | BENZODIOXOLE DERIVATIVES, COMPOSITIONS COMPRISING THE SAME, AND THE USE OF THE SAME FOR THE MANUFACTURE OF MEDICAMENTS | Eisai Co., Ltd. (JP) | 1992-11-25 | — | — | EP | disclosed |
| US-5110956-A | Liver disorders | EISAI CO., LTD. (JP) | 1992-05-05 | — | — | US | disclosed |
| EP-0281098-A1 | Benzodioxole derivatives, compositions comprising the same, and the use of the same for the manufacture of medicaments | Eisai Co., Ltd. (JP) | 1988-09-07 | — | — | EP | disclosed |
| JP-S63201168-A | PYRIDYLMETHYLSULFIDE DERIVATIVE | MECT CORP | 1988-08-19 | — | — | JP | disclosed |
| US-3985908-A | 3-Furyl sulfides and foodstuff flavor compositions comprising same | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1976-10-12 | — | — | US | disclosed |