Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.47 |
| ▸ | NTSR2 | O95665 | 4/20 | 0.43 |
| ▸ | NTSR1 | P30989 | 4/20 | 0.43 |
| ▸ | SORT1 | Q99523 | 4/20 | 0.43 |
| ▸ | XIAP | P98170 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 3/20 | 0.42 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.42 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.42 |
| ▸ | FAP | Q12884 | 2/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10419943 | 0.82 | ELANE (0.47) | ELANEDPP4DPP8ACEACE2 | |
| SCHEMBL10419941 | 0.82 | ELANE (0.47) | ELANEDPP4DPP8ACEACE2 | |
| SCHEMBL10702151 | 0.81 | DPP4 (0.52) | ELANENTSR2NTSR1SORT1XIAP | |
| SCHEMBL29350414 | 0.81 | XIAP (0.56) | ELANENTSR2NTSR1SORT1XIAP | |
| SCHEMBL10702146 | 0.81 | DPP4 (0.52) | ELANENTSR2NTSR1SORT1XIAP | |
| SCHEMBL30490609 | 0.80 | DPP4 (0.50) | ELANEXIAPDPP4DPP8DPP9 | |
| SCHEMBL31206270 | 0.77 | XIAP (0.66) | NTSR2NTSR1SORT1XIAPDPP4 | |
| SCHEMBL16702238 | 0.77 | XIAP (0.52) | NTSR2NTSR1SORT1XIAPDPP4 | |
| SCHEMBL16702590 | 0.77 | XIAP (0.52) | NTSR2NTSR1SORT1XIAPDPP4 | |
| SCHEMBL16701230 | 0.77 | XIAP (0.52) | NTSR2NTSR1SORT1XIAPDPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0078167-A1 | New N-nitroso-N-(beta-chloro-ethyl)-carbamoyl peptides | CHINOIN Gyogyszer és Vegyészeti Termékek Gyára RT. (HU) | 1983-05-04 | — | — | EP | disclosed |