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SCHEMBL10419941

SCHEMBL10419941

CCCCOC(=O)NC(CCCCN)C(=O)N1CCCC1C(=O)NC(C(N)=O)C(C)C

nearest known ligand 0.48

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ ELANE P08246 1/20 0.47
▸ ACE P12821 2/20 0.46
▸ ACE2 Q9BYF1 2/20 0.46
▸ CAPN1 P07384 4/20 0.43
▸ APLNR P35414 1/20 0.43
▸ STAT6 P42226 1/20 0.41
▸ DPP4 P27487 1/20 0.41
▸ DPP8 Q6V1X1 1/20 0.41
▸ CTSB P07858 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10419943 1.00 ELANE (0.47) ELANEACEACE2CAPN1APLNR
SCHEMBL10419938 0.90 ACE (0.45) ELANEACEACE2APLNRSTAT6
SCHEMBL10419940 0.90 ACE (0.45) ELANEACEACE2APLNRSTAT6
SCHEMBL28665808 0.85 ITGB3 (0.49) ELANEACEACE2CAPN1APLNR
SCHEMBL7324427 0.85 ACE (0.57) ACEACE2DPP4DPP8
SCHEMBL13448495 0.85 ITGB3 (0.49) ELANEACEACE2CAPN1APLNR
SCHEMBL13795060 0.85 ITGB3 (0.49) ELANEACEACE2CAPN1APLNR
SCHEMBL30342385 0.84 CAPN1 (0.45) ELANEACECAPN1APLNRSTAT6
SCHEMBL11203117 0.82 ELANE (0.47) ELANEACEACE2DPP4DPP8
SCHEMBL10702151 0.80 DPP4 (0.52) ELANEDPP4DPP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4950651-A Leukemia; antitumer agents CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA R.T. (HU) 1990-08-21 — — US disclosed
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