Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15197080 | 0.88 | MAPT (0.64) | MAPTRAB9AMEN1KMT2ALMNA | |
| SCHEMBL6932064 | 0.84 | MAPT (0.59) | MAPTRAB9AMEN1KMT2ALMNA | |
| SCHEMBL27616186 | 0.84 | MAPT (0.59) | MAPTRAB9AMEN1KMT2ALMNA | |
| SCHEMBL18660182 | 0.84 | MEN1 (0.62) | MAPTRAB9AMEN1KMT2AL3MBTL1 | |
| SCHEMBL9386081 | 0.82 | HDAC3 (0.64) | MAPTRAB9AMEN1KMT2ALMNA | |
| SCHEMBL28909121 | 0.82 | CYP1A1 (0.67) | MAPTMEN1KMT2ATP53CYP1A1 | |
| SCHEMBL22397597 | 0.82 | KMT2A (0.70) | MAPTRAB9AMEN1KMT2ALMNA | |
| SCHEMBL31473065 | 0.82 | HDAC1 (0.63) | MAPTRAB9AMEN1KMT2AL3MBTL1 | |
| SCHEMBL18660183 | 0.82 | HDAC1 (0.63) | MAPTRAB9AMEN1KMT2AL3MBTL1 | |
| SCHEMBL9358417 | 0.82 | MAPT (0.57) | MAPTRAB9AMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4415572-A | CARDIOTONIC AND INOTROPIC AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1983-11-15 | — | — | US | disclosed |