Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | APEX1 | P27695 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | SNCA | P37840 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 2/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL28348291 | 0.93 | MAPT (0.52) | MAPTRAB9AMEN1KMT2ALMNA | |
| SCHEMBL15267699 | 0.89 | KMT2A (0.60) | MAPTRAB9AMEN1KMT2ALMNA | |
| SCHEMBL11203302 | 0.84 | MAPT (0.55) | MAPTRAB9AMEN1KMT2ALMNA | |
| SCHEMBL15197080 | 0.83 | MAPT (0.64) | MAPTRAB9AMEN1KMT2ALMNA | |
| SCHEMBL11717080 | 0.81 | MAPT (0.61) | MAPTRAB9AMEN1KMT2ALMNA | |
| SCHEMBL11717085 | 0.81 | MAPT (0.61) | MAPTRAB9AMEN1KMT2ALMNA | |
| SCHEMBL1039601 | 0.81 | KMT2A (0.76) | RAB9AMEN1KMT2ALMNATDP1 | |
| SCHEMBL7888049 | 0.81 | CYP1A1 (0.60) | MAPTRAB9AMEN1KMT2ALMNA | |
| SCHEMBL6934242 | 0.81 | RAB9A (0.61) | MAPTRAB9AMEN1KMT2ALMNA | |
| SCHEMBL4548528 | 0.80 | TPSAB1 (0.48) | MEN1KMT2APOLBGAAHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0859000-B1 | Isoxazole amide and crotonamid derivatives and drug and diagnostic uses thereof | AVENTIS PHARMA GMBH (DE) | 2003-01-22 | — | — | EP | claimed |
| US-5977151-A | ANTITUMOR | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-11-02 | — | — | US | claimed |
| WO-2018068357-A1 | NOVEL SIRT2 PROTEIN INHIBITOR AND PHARMACEUTICAL USE THEREOF | 西华大学 | 2018-04-19 | — | — | WO | disclosed |
| US-20090163465-A1 | Pyrimidines as PLK inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-06-25 | — | — | US | disclosed |
| US-7521457-B2 | Pyrimidines as PLK inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-04-21 | — | — | US | disclosed |
| US-6265588-B1 | USE AS PHARMACEUTICALS; AS AN ANTIGEN FOR PRODUCTION OF ANTIBODIES AND IN DIAGNOSIS AND PURIFICATION | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2001-07-24 | — | — | US | disclosed |
| US-6121479-A | ANTIINFLAMMATORY AND ANTICARCINOGENIC AGENTS; AUTOIMMUNE DISEASES | HOECHST AKTIENGESELLSCHAFT (DE) | 2000-09-19 | — | — | US | disclosed |
| US-5977151-A | ANTITUMOR | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-11-02 | — | — | US | disclosed |
| US-4080321-A | COLORFASTNESS | HOECHST AKTIENGESELLSCHAFT (DT) | 1978-03-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090163465-A1 | Pyrimidines as PLK inhibitors | PLK2, PLK3, TYMP | MAPT 2912/4885RAB9A 1822/4885MEN1 4552/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.