SCHEMBL11203444

SCHEMBL11203444

Cc1ccc(NC(C(=O)O)C(C)C)cc1C

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.47
DGAT1 O75907 1/20 0.47
CSGALNACT1 Q8TDX6 1/20 0.46
TDP1 Q9NUW8 1/20 0.45
TSHR P16473 1/20 0.44
RECQL P46063 1/20 0.44
TAS1R3 Q7RTX0 1/20 0.44
TAS1R1 Q7RTX1 1/20 0.44
NPC1 O15118 3/20 0.44
RAB9A P51151 3/20 0.44
KMT2A Q03164 3/20 0.44
KDM4E B2RXH2 1/20 0.43
FPR2 P25090 1/20 0.43
CYP1A2 P05177 1/20 0.43
MEN1 O00255 2/20 0.42
FKBP5 Q13451 1/20 0.42
SMN1; SMN2 Q16637 3/20 0.41
LMNA P02545 2/20 0.41
MAPT P10636 2/20 0.41
GAA P10253 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11203447 1.00 POLB (0.47) POLBDGAT1CSGALNACT1TDP1TSHR
SCHEMBL11203103 0.85 KDM4E (0.40) DGAT1CSGALNACT1NPC1RAB9AKMT2A
SCHEMBL11206673 0.85 FPR2 (0.47) POLBCSGALNACT1TDP1NPC1RAB9A
SCHEMBL11197874 0.85 RAB9A (0.47) POLBTDP1RECQLNPC1RAB9A
SCHEMBL11058766 0.85 KMT2A (0.49) NPC1RAB9AKMT2AKDM4EFPR2
SCHEMBL11200964 0.85 S1PR1 (0.44) CSGALNACT1NPC1RAB9AKMT2AKDM4E
SCHEMBL11206672 0.85 FPR2 (0.47) POLBCSGALNACT1TDP1NPC1RAB9A
SCHEMBL11203101 0.85 KDM4E (0.40) DGAT1CSGALNACT1NPC1RAB9AKMT2A
SCHEMBL11200962 0.85 S1PR1 (0.44) CSGALNACT1NPC1RAB9AKMT2AKDM4E
SCHEMBL11203097 0.85 KMT2A (0.49) NPC1RAB9AKMT2AKDM4EFPR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4411912-A Insecticidal isovaleric acid esters ZOECON CORPORATION (US) 1983-10-25 US disclosed
US-4243819-A Substituted amino acids ZOECON CORPORATION (US) 1981-01-06 US disclosed