Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 2/20 | 0.37 |
| ▸ | MMP9 | P14780 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CTSC | P53634 | 5/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11352807 | 1.00 | THRB (0.39) | THRBMEN1KMT2AMMP2MMP9 | |
| SCHEMBL11203449 | 1.00 | THRB (0.39) | THRBMEN1KMT2AMMP2MMP9 | |
| SCHEMBL11203445 | 1.00 | THRB (0.39) | THRBMEN1KMT2AMMP2MMP9 | |
| SCHEMBL11208018 | 1.00 | THRB (0.39) | THRBMEN1KMT2AMMP2MMP9 | |
| SCHEMBL3623530 | 0.85 | ALDH1A1 (0.45) | ALDH1A1LMNAEPHX1CYP1A2CYP3A4 | |
| SCHEMBL29250547 | 0.85 | ALDH1A1 (0.45) | ALDH1A1LMNAEPHX1CYP1A2CYP3A4 | |
| SCHEMBL2061686 | 0.80 | GRM4 (0.45) | THRBMEN1KMT2AMMP2MMP9 | |
| SCHEMBL2061687 | 0.80 | GRM4 (0.45) | THRBMEN1KMT2AMMP2MMP9 | |
| SCHEMBL2061690 | 0.80 | GRM4 (0.45) | THRBMEN1KMT2AMMP2MMP9 | |
| SCHEMBL5897133 | 0.77 | ALDH1A1 (0.36) | CA1CA2ALDH1A1LMNAEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0008936-B1 | PLATINUM COMPLEXES, PROCESSES FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USE AS MEDICAMENTS | Kidani, Yoshinori (JP) | 1983-02-16 | — | — | EP | disclosed |
| US-4255347-A | ANTITUMOR AGENTS | Kidani, Yoshinori (JP) | 1981-03-10 | — | — | US | disclosed |
| EP-0008936-A1 | Platinum complexes, processes for their preparation, pharmaceutical compositions containing them and their use as medicaments | Kidani, Yoshinori (JP) | 1980-03-19 | — | — | EP | disclosed |