Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | XDH | P47989 | 1/20 | 0.37 |
| ▸ | FADS1 | O60427 | 1/20 | 0.36 |
| ▸ | YTHDC1 | Q96MU7 | 2/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | FLT3 | P36888 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12736701 | 0.80 | MAPK1 (0.49) | KMT2AELANEFLT3ALDH1A1HTT | |
| SCHEMBL25283031 | 0.78 | LATS1 (0.39) | KMT2AELANEFLT3HTR2CMAPK1 | |
| SCHEMBL29648815 | 0.78 | MEN1 (0.47) | KMT2AFADS1FLT3EGFRKDR | |
| SCHEMBL9432534 | 0.77 | PDE4B (0.49) | KMT2AFADS1ALDH1A1EGFRPIM1 | |
| SCHEMBL12963987 | 0.76 | ELANE (0.40) | KMT2AELANEFLT3HTTCHEK1 | |
| SCHEMBL9432141 | 0.76 | CSNK2A1 (0.51) | KMT2AFLT3ALDH1A1PIM1 | |
| SCHEMBL3864384 | 0.76 | RAPGEF4 (0.38) | FADS1 | |
| SCHEMBL11312951 | 0.76 | ALDH1A1 (0.41) | KMT2AELANECYP2D6CYP2C19FLT3 | |
| SCHEMBL1182070 | 0.75 | HTR2C (0.50) | KMT2AELANECYP2D6CYP2C19FLT3 | |
| SCHEMBL15440490 | 0.73 | PDE5A (0.62) | KMT2AALDH1A1HTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0082023-A2 | Thienopyrimidine derivatives, their preparation and their medical use | SANKYO COMPANY LIMITED (JP) | 1983-06-22 | — | — | EP | disclosed |