Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNASE1 | P07998 | 1/20 | 0.62 |
| ▸ | TK1 | P04183 | 2/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | TK2 | O00142 | 8/20 | 0.50 |
| ▸ | TYMS | P04818 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11198667 | 0.92 | RNASE1 (0.52) | RNASE1TK1CYP1A2CYP3A4TSHR | |
| SCHEMBL11200741 | 0.91 | RNASE1 (0.70) | RNASE1TK1CYP1A2CYP3A4TSHR | |
| SCHEMBL11200745 | 0.91 | RNASE1 (0.70) | RNASE1TK1CYP1A2CYP3A4TSHR | |
| SCHEMBL11200750 | 0.91 | RNASE1 (0.70) | RNASE1TK1CYP1A2CYP3A4TSHR | |
| SCHEMBL11201280 | 0.85 | TK1 (0.59) | RNASE1TK1CYP1A2CYP3A4TSHR | |
| SCHEMBL11201271 | 0.85 | TK1 (0.59) | RNASE1TK1CYP1A2CYP3A4TSHR | |
| SCHEMBL11201275 | 0.85 | TK1 (0.59) | RNASE1TK1CYP1A2CYP3A4TSHR | |
| SCHEMBL11288942 | 0.84 | TK1 (0.70) | RNASE1TK1CYP1A2CYP3A4TSHR | |
| SCHEMBL11288948 | 0.84 | TK1 (0.70) | RNASE1TK1CYP1A2CYP3A4TSHR | |
| SCHEMBL11288944 | 0.84 | TK1 (0.70) | RNASE1TK1CYP1A2CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0082668-A1 | 5-(2-Halogenovinyl)-2'-deoxyuridine derivatives, processes for their preparation, pharmaceutical compositions containing them and their use in treating viral infections | BEECHAM GROUP PLC (GB) | 1983-06-29 | — | — | EP | disclosed |