Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | CETP | P11597 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | SOAT1 | P35610 | 3/20 | 0.48 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.48 |
| ▸ | EP300 | Q09472 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6237186 | 0.98 | CETP (0.51) | MEN1GAAKMT2ANPC1RAB9A | |
| SCHEMBL11199473 | 0.95 | MEN1 (0.50) | MEN1GAAKMT2ANPC1RAB9A | |
| SCHEMBL6464495 | 0.88 | ADORA2A (0.56) | MEN1GAAKMT2ANPC1RAB9A | |
| SCHEMBL3422728 | 0.81 | GAA (0.55) | MEN1GAAKMT2ANPC1RAB9A | |
| Hydrochloric Acid SCHEMBL28317066 | 0.80 | GAA (0.54) | MEN1GAAKMT2ANPC1RAB9A | |
| SCHEMBL27489667 | 0.77 | GAA (0.47) | MEN1GAAKMT2ANPC1RAB9A | |
| SCHEMBL8938895 | 0.76 | L3MBTL1 (0.50) | MEN1GAAKMT2ANPC1RAB9A | |
| SCHEMBL7102449 | 0.75 | L3MBTL1 (0.56) | MEN1GAAKMT2ANPC1RAB9A | |
| SCHEMBL8269685 | 0.75 | USP2 (0.85) | MEN1GAAKMT2ASMN1; SMN2LMNA | |
| SCHEMBL9382436 | 0.74 | GAA (0.51) | MEN1GAAKMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0078860-A1 | New 5-(N-alkyl-N-acyl-amino)-thiophen-2-carboxylic acid derivatives, process for producing the same and pharmaceutical compounds containing the same | A. Nattermann & Cie. GmbH (DE) | 1983-05-18 | — | — | EP | disclosed |
| US-4349686-A | 5-(N-Alkyl-N-acyl-amino)-thiophen-2-carboxylic acid derivatives | A. NATTERMANN & CIE GMBH (DE) | 1982-09-14 | — | — | US | disclosed |