Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.56 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 10/20 | 0.53 |
| ▸ | MEN1 | O00255 | 8/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.53 |
| ▸ | RAB9A | P51151 | 7/20 | 0.53 |
| ▸ | MAPT | P10636 | 7/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 6/20 | 0.53 |
| ▸ | NPC1 | O15118 | 5/20 | 0.53 |
| ▸ | TP53 | P04637 | 5/20 | 0.53 |
| ▸ | HTT | P42858 | 4/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11199473 | 0.90 | MEN1 (0.50) | ADORA2AADORA1ADORA3GAAMEN1 | |
| SCHEMBL11204255 | 0.88 | MEN1 (0.49) | GAAMEN1KMT2AHSD17B10RAB9A | |
| SCHEMBL6237186 | 0.87 | CETP (0.51) | GAAMEN1KMT2AHSD17B10RAB9A | |
| SCHEMBL3422728 | 0.85 | GAA (0.55) | ADORA2AADORA1ADORA3GAAMEN1 | |
| Hydrochloric Acid SCHEMBL28317066 | 0.84 | GAA (0.54) | ADORA2AADORA1ADORA3GAAMEN1 | |
| SCHEMBL27489667 | 0.81 | GAA (0.47) | GAAMEN1KMT2AHSD17B10RAB9A | |
| SCHEMBL8853392 | 0.78 | CASP3 (0.57) | GAAMEN1KMT2AHSD17B10RAB9A | |
| SCHEMBL9382436 | 0.78 | GAA (0.51) | GAAMEN1KMT2AHSD17B10RAB9A | |
| Acetic Acid SCHEMBL10585627 | 0.76 | GAA (0.49) | GAAMEN1KMT2AHSD17B10RAB9A | |
| SCHEMBL21067510 | 0.75 | GAA (0.49) | GAAMEN1KMT2AHSD17B10RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108569977-A | A kind of preparation method of primary fatty amides | 中国科学技术大学 | 2018-09-25 | — | — | CN | disclosed |
| EP-3071036-A1 | PESTICIDAL COMPOSITIONS AND RELATED METHODS | Dow AgroSciences LLC (US) | 2016-09-28 | — | — | EP | disclosed |
| WO-2015061165-A1 | PESTICIDAL COMPOSITIONS AND RELATED METHODS | DOW AGROSCIENCES LLC (US) | 2015-04-30 | — | — | WO | disclosed |
| US-20050197350-A1 | Novel quinoline, tetrahydroquinazoline, and pyrimidine derivatives and methods of treatment related to the use thereof | TAISHO PHARMACEUTICAL CO., LTD. | 2005-09-08 | — | — | US | disclosed |
| EP-0078860-A1 | New 5-(N-alkyl-N-acyl-amino)-thiophen-2-carboxylic acid derivatives, process for producing the same and pharmaceutical compounds containing the same | A. Nattermann & Cie. GmbH (DE) | 1983-05-18 | — | — | EP | disclosed |
| US-4349686-A | 5-(N-Alkyl-N-acyl-amino)-thiophen-2-carboxylic acid derivatives | A. NATTERMANN & CIE GMBH (DE) | 1982-09-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050197350-A1 | Novel quinoline, tetrahydroquinazoline, and pyrimidine derivatives and methods of treatment related to the use thereof | HCRTR2, MCHR1, MCHR2 | ADORA2A 243/4885ADORA1 369/4885ADORA3 244/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.