Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.74 |
| ▸ | MAPT | P10636 | 3/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.74 |
| ▸ | MME | P08473 | 5/20 | 0.43 |
| ▸ | KDM4A | O75164 | 1/20 | 0.43 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.41 |
| ▸ | GNPAT | O15228 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 3/20 | 0.40 |
| ▸ | CPA1 | P15085 | 3/20 | 0.40 |
| ▸ | ACE2 | Q9BYF1 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 2/20 | 0.39 |
| ▸ | CTSB | P07858 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7311462 | 0.86 | MAPT (1.00) | ALDH1A1MAPTKDM4EDNMT1MEN1 | |
| SCHEMBL7311455 | 0.86 | MAPT (1.00) | ALDH1A1MAPTKDM4EDNMT1MEN1 | |
| SCHEMBL1158294 | 0.85 | MAPT (0.71) | ALDH1A1MAPTKDM4EKDM4ADNMT1 | |
| SCHEMBL1158293 | 0.85 | MAPT (0.71) | ALDH1A1MAPTKDM4EKDM4ADNMT1 | |
| SCHEMBL10431037 | 0.79 | MAPT (0.65) | ALDH1A1MAPTKDM4EMMEKDM4A | |
| SCHEMBL10431038 | 0.79 | MAPT (0.65) | ALDH1A1MAPTKDM4EMMEKDM4A | |
| SCHEMBL7312481 | 0.77 | MAPT (0.78) | ALDH1A1MAPTKDM4EDNMT1MEN1 | |
| SCHEMBL7312478 | 0.77 | MAPT (0.78) | ALDH1A1MAPTKDM4EDNMT1MEN1 | |
| SCHEMBL11226801 | 0.77 | MAPT (0.78) | ALDH1A1MAPTKDM4EDNMT1MEN1 | |
| SCHEMBL7540298 | 0.77 | MAPT (0.81) | ALDH1A1MAPTKDM4EDNMT1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0017536-B1 | PROCESS FOR THE PREPARATION OF SOMATOSTATINE | SANOFI S.A. (FR) | 1983-03-23 | — | — | EP | disclosed |
| US-4337194-A | MULTISTEP, WITH PURIFICATION BY WASHING AFTER EACH COUPLING | C. M. INDUSTRIES (FR) | 1982-06-29 | — | — | US | disclosed |
| EP-0017536-A2 | Process for the preparation of somatostatine | SANOFI S.A. (FR) | 1980-10-15 | — | — | EP | disclosed |