Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 1.00 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALPG | P10696 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CTSD | P07339 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7311462 | 1.00 | MAPT (1.00) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL7540298 | 0.90 | MAPT (0.81) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL7312481 | 0.88 | MAPT (0.78) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL7312478 | 0.88 | MAPT (0.78) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL11226801 | 0.88 | MAPT (0.78) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL11204337 | 0.86 | ALDH1A1 (0.74) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL1158294 | 0.83 | MAPT (0.71) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL1158293 | 0.83 | MAPT (0.71) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL7336052 | 0.82 | MAPT (0.70) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL11700361 | 0.81 | MAPT (0.69) | MAPTALDH1A1KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4508645-A | CYCLIC OLIGOPEPTIDE CONTAINING PENICILLAMINE RESIDE | CESKOSLOVENSKA AKADEMIE VED (CS) | 1985-04-02 | — | — | US | disclosed |