SCHEMBL1158293

SCHEMBL1158293

O=C(O)[C@H](Cc1ccccc1)NSc1ccccc1[N+](=O)[O-]

nearest known ligand 0.71

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.71
ALDH1A1 P00352 5/20 0.71
KDM4E B2RXH2 2/20 0.71
DNMT1 P26358 1/20 0.52
GAA P10253 3/20 0.50
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
KDM4A O75164 1/20 0.47
NPSR1 Q6W5P4 2/20 0.46
LMNA P02545 2/20 0.46
ALPG P10696 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
CPA1 P15085 6/20 0.43
CYP1A2 P05177 1/20 0.43
MMP2 P08253 2/20 0.42
MMP9 P14780 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1158294 1.00 MAPT (0.71) MAPTALDH1A1KDM4EDNMT1GAA
SCHEMBL10431037 0.93 MAPT (0.65) MAPTALDH1A1KDM4EDNMT1GAA
SCHEMBL10431038 0.93 MAPT (0.65) MAPTALDH1A1KDM4EDNMT1GAA
SCHEMBL7318856 0.86 MAPT (0.57) MAPTALDH1A1KDM4EDNMT1GAA
SCHEMBL7540298 0.85 MAPT (0.81) MAPTALDH1A1KDM4EDNMT1GAA
SCHEMBL11204337 0.85 ALDH1A1 (0.74) MAPTALDH1A1KDM4EDNMT1GAA
SCHEMBL7311455 0.83 MAPT (1.00) MAPTALDH1A1KDM4EDNMT1GAA
SCHEMBL7336052 0.83 MAPT (0.70) MAPTALDH1A1KDM4EDNMT1GAA
SCHEMBL7311462 0.83 MAPT (1.00) MAPTALDH1A1KDM4EDNMT1GAA
SCHEMBL7312481 0.81 MAPT (0.78) MAPTALDH1A1KDM4EDNMT1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7888417-B2 core or the layer includes a composition formed from a base polymer, a crosslink initiator, and at least one additive; additive has at least one carbon-oxygen-boron linkage, carbon in the linkage being a secondary or tertiary carbon; enhances coefficient of restitution and/or reduces compression of core ACUSHNET COMPANY (US) 2011-02-15 US disclosed
US-20080261722-A1 COMPOSITIONS FOR USE IN GOLF BALLS ACUSHNET COMPANY 2008-10-23 US disclosed
US-20080227567-A1 COMPOSITIONS FOR USE IN GOLF BALLS ACUSHNET COMPANY 2008-09-18 US disclosed
US-20080176678-A1 Compositions for Use in Golf Balls ACUSHNET COMPANY 2008-07-24 US disclosed
US-7361711-B2 Compositions for use in golf balls ACUSHNET COMPANY (US) 2008-04-22 US disclosed
US-7358309-B2 core or the layer includes a composition formed from a base polymer, a crosslink initiator, and at least one additive; additive has at least one carbon-oxygen-boron linkage, carbon in the linkage being a secondary or tertiary carbon; enhances coefficient of restitution and/or reduces compression of core ACUSHNET COMPANY (US) 2008-04-15 US disclosed
US-7358310-B2 Compositions for use in golf balls ACUSHNET COMPANY (US) 2008-04-15 US disclosed
US-7358308-B2 Compositions for use in golf balls ACUSHNET COMPANY (US) 2008-04-15 US disclosed
US-20060281586-A1 Compositions for use in golf balls JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2006-12-14 US disclosed
US-20060281587-A1 Compositions for use in golf balls JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2006-12-14 US disclosed
US-20050245657-A1 Compositions for use in golf balls JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2005-11-03 US disclosed
US-20050245652-A1 Compositions for use in golf balls JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2005-11-03 US disclosed
US-4508645-A CYCLIC OLIGOPEPTIDE CONTAINING PENICILLAMINE RESIDE CESKOSLOVENSKA AKADEMIE VED (CS) 1985-04-02 US disclosed
US-4013565-A MEMBRANES RHONE-POULENC S.A. (FR) 1977-03-22 US disclosed