SCHEMBL11204451

SCHEMBL11204451

OOCc1cccc(Oc2ccccc2)c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP1 P03956 2/20 0.55
FFAR1 O14842 4/20 0.54
FFAR4 Q5NUL3 2/20 0.54
MMP2 P08253 1/20 0.54
MMP9 P14780 1/20 0.54
MMP12 P39900 1/20 0.54
CETP P11597 1/20 0.50
TSHR P16473 1/20 0.48
HSD17B10 Q99714 1/20 0.48
KDM4E B2RXH2 3/20 0.47
ALDH1A1 P00352 3/20 0.47
HTT P42858 2/20 0.47
TDP1 Q9NUW8 1/20 0.47
HPGD P15428 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
AKR1C3 P42330 1/20 0.47
LTA4H P09960 2/20 0.47
MAOB P27338 1/20 0.47
NR1H2 P55055 1/20 0.47
BAX Q07812 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2354114 0.84 TSHR (0.56) MMP1FFAR1FFAR4MMP2MMP9
SCHEMBL9491438 0.82 FFAR1 (0.68) FFAR1FFAR4MAOB
SCHEMBL30521657 0.81 FFAR1 (0.50) MMP1FFAR1FFAR4MMP2MMP9
SCHEMBL1715197 0.81 IDO1 (0.65) FFAR1FFAR4MAOB
SCHEMBL2093733 0.81 FFAR1 (0.50) MMP1FFAR1FFAR4MMP2MMP9
SCHEMBL2093737 0.81 KDM4E (0.55) MMP1FFAR1FFAR4CETPTSHR
SCHEMBL358425 0.80 LTA4H (0.67) FFAR1FFAR4TSHRHSD17B10KDM4E
SCHEMBL29661187 0.80 LTA4H (0.67) FFAR1FFAR4TSHRHSD17B10KDM4E
SCHEMBL8896665 0.79 TSHR (0.55) TSHRHSD17B10KDM4EALDH1A1HTT
Hydrochloric Acid SCHEMBL9716600 0.79 IDO1 (0.66) LTA4HMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-58072532-A None JP disclosed
JP-S5872532-A DECOMPOSITION OF HYDROPEROXIDE COMPOUND UBE IND LTD 1983-04-30 JP disclosed