SCHEMBL8896665

SCHEMBL8896665

c1ccc(Oc2cccc(Cc3cccc(Oc4ccccc4)c3)c2)cc1

nearest known ligand 0.63

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.55
LTA4H P09960 2/20 0.55
MAOB P27338 1/20 0.54
KDM4E B2RXH2 4/20 0.53
ALDH1A1 P00352 4/20 0.53
HTT P42858 2/20 0.53
TDP1 Q9NUW8 1/20 0.53
HPGD P15428 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
P2RX3 P56373 1/20 0.49
HSD17B10 Q99714 1/20 0.49
MEN1 O00255 1/20 0.49
KMT2A Q03164 1/20 0.49
SRD5A2 P31213 1/20 0.48
AKR1C3 P42330 1/20 0.48
CALM1 P0DP23 1/20 0.48
TRPV6 Q9H1D0 1/20 0.47
FDFT1 P37268 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23312282 0.96 ALDH1A1 (0.50) TSHRLTA4HMAOBKDM4EALDH1A1
SCHEMBL22550294 0.95 CALM1 (0.55) TSHRLTA4HMAOBKDM4EALDH1A1
SCHEMBL9816693 0.94 SRD5A2 (0.58) TSHRLTA4HMAOBKDM4EALDH1A1
Ethylene Glycol SCHEMBL28545403 0.88 TSHR (0.51) TSHRLTA4HKDM4EALDH1A1HTT
SCHEMBL8939741 0.87 KDM4E (0.44) TSHRLTA4HMAOBKDM4EALDH1A1
SCHEMBL27630414 0.87 LTA4H (0.57) LTA4HKDM4EALDH1A1HTTSMN1; SMN2
SCHEMBL29436315 0.84 ALDH1A1 (0.70) TSHRMAOBKDM4EALDH1A1HTT
SCHEMBL311611 0.84 ALDH1A1 (0.70) TSHRMAOBKDM4EALDH1A1HTT
SCHEMBL9816690 0.83 KDM4E (0.55) MAOBKDM4EALDH1A1HTTTDP1
SCHEMBL21549624 0.83 MAOB (0.67) MAOBALDH1A1SMN1; SMN2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0531715-B1 Process for producing alcohols and ketones SUMITOMO CHEMICAL CO (JP) 1997-11-05 EP disclosed
US-5426237-A Oxidation of straight, branched or cyclic alkanes and benzene derivatives in presence of transition metal catalyst and aldehyde SUMITOMO CHEMICAL CO., LTD. (JP) 1995-06-20 US disclosed
EP-0531715-A1 Process for producing alcohols and ketones SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-03-17 EP disclosed