Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.42 |
| ▸ | IKBKB | O14920 | 2/20 | 0.38 |
| ▸ | CHUK | O15111 | 1/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.38 |
| ▸ | EPHA3 | P29320 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | KHK | P50053 | 1/20 | 0.36 |
| ▸ | CETP | P11597 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP4 | P49662 | 1/20 | 0.36 |
| ▸ | CASP5 | P51878 | 1/20 | 0.36 |
| ▸ | PLK4 | O00444 | 1/20 | 0.36 |
| ▸ | PAK4 | O96013 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 2/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.35 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11201826 | 0.93 | CETP (0.42) | P2RY12IKBKBCHUKPDGFRAEPHA3 | |
| SCHEMBL11199721 | 0.91 | P2RY12 (0.50) | P2RY12HTR2CKHKCASP1CASP4 | |
| SCHEMBL11205063 | 0.83 | KDM4E (0.47) | P2RY12IKBKBCHUKPDGFRAEPHA3 | |
| SCHEMBL11206200 | 0.83 | HTR3A (0.38) | P2RY12KDM4EBRD4ALDH1A1HTR3A | |
| SCHEMBL11197165 | 0.82 | P2RY12 (0.49) | P2RY12HTR2CCASP1CASP4CASP5 | |
| SCHEMBL11202691 | 0.82 | KHK (0.42) | HTR2CKHKCASP1CASP4CASP5 | |
| Hydrochloric Acid SCHEMBL11201994 | 0.81 | KHK (0.41) | HTR2CKHKCASP1CASP4CASP5 | |
| SCHEMBL11203169 | 0.81 | P2RY12 (0.48) | P2RY12HTR2CKHKKDM4EALDH1A1 | |
| SCHEMBL11204697 | 0.80 | P2RY12 (0.47) | P2RY12HTR2CKHKKDM4EALDH1A1 | |
| SCHEMBL11203359 | 0.79 | P2RY12 (0.47) | P2RY12KHKKDM4EALDH1A1HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0082023-A2 | Thienopyrimidine derivatives, their preparation and their medical use | SANKYO COMPANY LIMITED (JP) | 1983-06-22 | — | — | EP | disclosed |