Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | MMP1 | P03956 | 2/20 | 0.36 |
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
| ▸ | MMP9 | P14780 | 2/20 | 0.36 |
| ▸ | MMP8 | P22894 | 2/20 | 0.36 |
| ▸ | MMP13 | P45452 | 2/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.32 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.32 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7779621 | 0.77 | THRB (0.62) | THRBLMNACA2CA1MMP1 | |
| SCHEMBL465610 | 0.77 | THRB (0.62) | THRBLMNACA2CA1MMP1 | |
| SCHEMBL703138 | 0.77 | THRB (0.62) | THRBLMNACA2CA1MMP1 | |
| SCHEMBL11536932 | 0.77 | THRB (0.48) | THRBLMNACA2CA1MMP1 | |
| SCHEMBL428315 | 0.77 | THRB (0.62) | THRBLMNACA2CA1MMP1 | |
| SCHEMBL7782672 | 0.77 | THRB (0.62) | THRBLMNACA2CA1MMP1 | |
| SCHEMBL536269 | 0.77 | THRB (0.62) | THRBLMNACA2CA1MMP1 | |
| SCHEMBL9110820 | 0.77 | THRB (0.62) | THRBLMNACA2CA1MMP1 | |
| SCHEMBL4595076 | 0.77 | THRB (0.62) | THRBLMNACA2CA1MMP1 | |
| SCHEMBL957654 | 0.77 | THRB (0.62) | THRBLMNACA2CA1MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4401829-A | Process for the preparation of perfluorinated carboxylic acid fluorides | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-08-30 | — | — | US | disclosed |