Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 15/20 | 0.36 |
| ▸ | CA1 | P00915 | 14/20 | 0.36 |
| ▸ | MMP1 | P03956 | 2/20 | 0.36 |
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
| ▸ | MMP9 | P14780 | 2/20 | 0.36 |
| ▸ | MMP8 | P22894 | 2/20 | 0.36 |
| ▸ | MMP13 | P45452 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.32 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.32 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL957476 | 1.00 | THRB (0.62) | THRBLMNACA2CA1MMP1 | |
| SCHEMBL955674 | 1.00 | THRB (0.62) | THRBLMNACA2CA1MMP1 | |
| SCHEMBL7779859 | 1.00 | THRB (0.62) | THRBLMNACA2CA1MMP1 | |
| SCHEMBL536269 | 1.00 | THRB (0.62) | THRBLMNACA2CA1MMP1 | |
| SCHEMBL428315 | 1.00 | THRB (0.62) | THRBLMNACA2CA1MMP1 | |
| SCHEMBL465610 | 1.00 | THRB (0.62) | THRBLMNACA2CA1MMP1 | |
| SCHEMBL953593 | 1.00 | THRB (0.62) | THRBLMNACA2CA1MMP1 | |
| SCHEMBL7779621 | 1.00 | THRB (0.62) | THRBLMNACA2CA1MMP1 | |
| SCHEMBL957654 | 1.00 | THRB (0.62) | THRBLMNACA2CA1MMP1 | |
| Water SCHEMBL11048628 | 0.97 | THRB (0.59) | THRBLMNACA2CA1MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0825167-B1 | COMPOUNDS AND SURFACTANTS | ASAHI DENKA KOGYO KK (JP) | 2001-10-04 | — | — | EP | disclosed |
| US-5929290-A | A HYDROPHILIC POLYETHER HAVING A FLUORO-SUBSTITUTED ALKYL END GROUP AND A (METH)ALLYL GLYCIDYL END GROUP; EMULSIFIERS AND DISPERSANTS FOR EMULSION AND SUSPENSION POLYMERIZATION, RESP.; RESIN REFORMING AGENTS; ANTISOILANTS FOR POLYESTERS | ASAHI DENKA KOGYO K. K. (JP) | 1999-07-27 | — | — | US | disclosed |
| EP-0825167-A1 | COMPOUNDS AND SURFACTANTS | ASAHI DENKA KOGYO KABUSHIKI KAISHA (JP) | 1998-02-25 | — | — | EP | disclosed |