Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 15/20 | 0.50 |
| ▸ | DDB1 | Q16531 | 13/20 | 0.50 |
| ▸ | IKZF3 | Q9UKT9 | 2/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | TNF | P01375 | 1/20 | 0.39 |
| ▸ | IL1B | P01584 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5154520 | 0.79 | ACE (0.51) | CRBNDDB1IKZF3CHRM2ALDH1A1 | |
| SCHEMBL5154587 | 0.79 | ACE (0.51) | CRBNDDB1IKZF3CHRM2ALDH1A1 | |
| SCHEMBL5154528 | 0.79 | ACE (0.51) | CRBNDDB1IKZF3CHRM2ALDH1A1 | |
| SCHEMBL5158143 | 0.79 | ACE (0.51) | CRBNDDB1IKZF3CHRM2ALDH1A1 | |
| SCHEMBL5154165 | 0.79 | ACE (0.51) | CRBNDDB1IKZF3CHRM2ALDH1A1 | |
| SCHEMBL13364982 | 0.77 | CRBN (0.54) | CRBNDDB1IKZF3CHRM2ALDH1A1 | |
| SCHEMBL13271120 | 0.77 | CRBN (0.54) | CRBNDDB1IKZF3CHRM2ALDH1A1 | |
| SCHEMBL27861219 | 0.77 | CRBN (0.54) | CRBNDDB1IKZF3CHRM2ALDH1A1 | |
| SCHEMBL5507404 | 0.77 | CRBN (0.54) | CRBNDDB1IKZF3CHRM2ALDH1A1 | |
| SCHEMBL845548 | 0.77 | CRBN (0.54) | CRBNDDB1IKZF3CHRM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0094095-A2 | Bicyclic carboxylic acids and their alkyl and aralkyl esters | F. HOFFMANN-LA ROCHE AG (CH) | 1983-11-16 | — | — | EP | disclosed |