Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 17/20 | 0.54 |
| ▸ | DDB1 | Q16531 | 15/20 | 0.54 |
| ▸ | IKZF3 | Q9UKT9 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | TNF | P01375 | 1/20 | 0.42 |
| ▸ | IL1B | P01584 | 1/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.42 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28704521 | 0.83 | DDB1 (0.60) | CRBNDDB1IKZF3ALDH1A1CHRM2 | |
| SCHEMBL13364982 | 0.81 | CRBN (0.54) | CRBNDDB1IKZF3ALDH1A1CHRM2 | |
| SCHEMBL845548 | 0.81 | CRBN (0.54) | CRBNDDB1IKZF3ALDH1A1CHRM2 | |
| SCHEMBL13271120 | 0.81 | CRBN (0.54) | CRBNDDB1IKZF3ALDH1A1CHRM2 | |
| SCHEMBL4108316 | 0.78 | ALDH1A1 (0.51) | CRBNDDB1IKZF3ALDH1A1CHRM2 | |
| SCHEMBL4103132 | 0.77 | DDB1 (0.50) | CRBNDDB1IKZF3ALDH1A1CHRM2 | |
| SCHEMBL11205141 | 0.77 | CRBN (0.50) | CRBNDDB1IKZF3ALDH1A1CHRM2 | |
| SCHEMBL21792468 | 0.77 | CRBN (0.50) | CRBNDDB1IKZF3ALDH1A1CHRM2 | |
| SCHEMBL2919642 | 0.77 | CRBN (0.50) | CRBNDDB1IKZF3ALDH1A1CHRM2 | |
| SCHEMBL10281158 | 0.77 | CRBN (0.50) | CRBNDDB1IKZF3ALDH1A1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102370986-A | Pharmaceutical compositions containing hydroxymethyl neurosedyn derivatives as well as preparation and application thereof | TIANJIN HEMAY BIO TECH CO LTD | 2012-03-14 | — | — | CN | claimed |
| CN-102370986-A | Pharmaceutical compositions containing hydroxymethyl neurosedyn derivatives as well as preparation and application thereof | TIANJIN HEMAY BIO TECH CO LTD | 2012-03-14 | — | — | CN | disclosed |
| EP-1853302-A2 | ANTIANGIOGENIC AGENTS WITH ALDESLEUKIN | Novartis Vaccines and Diagnostics, Inc. (US) | 2007-11-14 | — | — | EP | disclosed |
| WO-2006089150-A2 | ANTIANGIOGENIC AGENTS WITH ALDESLEUKIN | NOVARTIS VACCINES AND DIAGNOSTICS INC. (US) | 2006-08-24 | — | — | WO | disclosed |