SCHEMBL11205371

SCHEMBL11205371

O=P(O)(O)Cc1cccc(Oc2ccc(C(F)(F)F)cc2Cl)c1

nearest known ligand 0.59

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ACP3 P15309 1/20 0.59
FFAR1 O14842 3/20 0.52
MRGPRX4 Q96LA9 11/20 0.48
PGK1 P00558 1/20 0.48
PGK2 P07205 1/20 0.48
STK39 Q9UEW8 1/20 0.46
MEN1 O00255 1/20 0.46
TTR P02766 1/20 0.46
PPOX P50336 1/20 0.46
KMT2A Q03164 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
PPARG P37231 1/20 0.46
PPARD Q03181 1/20 0.46
PPARA Q07869 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11204289 0.85 ACP3 (0.58) ACP3PGK1PGK2MEN1KMT2A
SCHEMBL11197033 0.84 FFAR1 (0.46) FFAR1MRGPRX4STK39PPARGPPARD
SCHEMBL10688351 0.84 FFAR1 (0.54) FFAR1MRGPRX4STK39MEN1TTR
SCHEMBL10693814 0.82 MRGPRX4 (0.52) FFAR1MRGPRX4STK39MEN1TTR
SCHEMBL10507700 0.82 FFAR1 (0.62) FFAR1MRGPRX4MEN1TTRPPOX
SCHEMBL10507578 0.82 FFAR1 (0.56) FFAR1MRGPRX4STK39MEN1TTR
SCHEMBL10482190 0.81 MRGPRX4 (0.51) FFAR1MRGPRX4MEN1TTRPPOX
SCHEMBL11260950 0.81 MRGPRX4 (0.51) FFAR1MRGPRX4STK39MEN1TTR
SCHEMBL10538095 0.80 NPSR1 (0.57) FFAR1MRGPRX4STK39MEN1TTR
SCHEMBL3523039 0.80 FFAR1 (0.77) FFAR1MRGPRX4MEN1TTRPPOX

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0077961-A2 Substituted 2-nitro-5-(4-trifluoromethyl-phenoxy) toluols, process for their preparation and their use as herbicides and plant growth regulators BAYER AG (DE) 1983-05-04 EP disclosed