SCHEMBL11260950

SCHEMBL11260950

FC(F)(F)c1ccc(Oc2cccc(CS)c2)c(Cl)c1

nearest known ligand 0.55

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MRGPRX4 Q96LA9 11/20 0.51
FFAR1 O14842 3/20 0.51
MAPT P10636 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
MEN1 O00255 1/20 0.45
TTR P02766 1/20 0.45
PPOX P50336 1/20 0.45
KMT2A Q03164 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
HTR2A P28223 1/20 0.43
SLC6A4 P31645 1/20 0.43
KCNH2 Q12809 1/20 0.43
PPARG P37231 1/20 0.43
PPARD Q03181 1/20 0.43
PPARA Q07869 1/20 0.43
STK39 Q9UEW8 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10693814 0.88 MRGPRX4 (0.52) MRGPRX4FFAR1MAPTNPSR1L3MBTL1
SCHEMBL10688351 0.86 FFAR1 (0.54) MRGPRX4FFAR1MAPTNPSR1L3MBTL1
SCHEMBL10482190 0.86 MRGPRX4 (0.51) MRGPRX4FFAR1MAPTNPSR1L3MBTL1
SCHEMBL10538095 0.85 NPSR1 (0.57) MRGPRX4FFAR1MAPTNPSR1L3MBTL1
SCHEMBL10508984 0.82 FFAR1 (0.53) MRGPRX4FFAR1MEN1TTRPPOX
SCHEMBL10507700 0.82 FFAR1 (0.62) MRGPRX4FFAR1MEN1TTRPPOX
SCHEMBL10507578 0.82 FFAR1 (0.56) MRGPRX4FFAR1MEN1TTRPPOX
SCHEMBL14018271 0.82 FFAR1 (0.48) MRGPRX4FFAR1MAPTNPSR1L3MBTL1
SCHEMBL11648951 0.81 FFAR1 (0.50) MRGPRX4FFAR1MAPTNPSR1L3MBTL1
SCHEMBL11205371 0.81 ACP3 (0.59) MRGPRX4FFAR1MEN1TTRPPOX

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0056119-A1 Substituted diphenyl ethers, herbicides containing them and their use as herbicides BASF Aktiengesellschaft (DE) 1982-07-21 EP disclosed