SCHEMBL10538095

SCHEMBL10538095

FC(F)(F)c1ccc(Oc2cccc(Oc3ccc(C(F)(F)F)cc3Cl)c2)c(Cl)c1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 2/20 0.57
MAPT P10636 1/20 0.57
L3MBTL1 Q9Y468 1/20 0.57
FFAR1 O14842 3/20 0.53
MEN1 O00255 1/20 0.52
TTR P02766 1/20 0.52
PPOX P50336 1/20 0.52
KMT2A Q03164 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
MRGPRX4 Q96LA9 6/20 0.50
STK39 Q9UEW8 1/20 0.49
HTR2A P28223 2/20 0.48
SLC6A4 P31645 2/20 0.48
KCNH2 Q12809 2/20 0.48
RAB9A P51151 1/20 0.47
EGFR P00533 2/20 0.46
ERBB2 P04626 2/20 0.46
ERBB3 P21860 2/20 0.46
ERBB4 Q15303 2/20 0.46
CYP1A2 P05177 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11046440 0.92 L3MBTL1 (0.70) NPSR1MAPTL3MBTL1FFAR1MEN1
SCHEMBL11648951 0.92 FFAR1 (0.50) NPSR1MAPTL3MBTL1FFAR1MEN1
SCHEMBL9132379 0.91 FFAR1 (0.49) NPSR1MAPTL3MBTL1FFAR1MEN1
SCHEMBL9003844 0.90 FFAR1 (0.60) NPSR1MAPTL3MBTL1FFAR1MEN1
SCHEMBL8813323 0.89 MRGPRX4 (0.61) NPSR1MAPTL3MBTL1FFAR1MEN1
SCHEMBL11121304 0.89 STK39 (0.50) NPSR1MAPTL3MBTL1FFAR1MEN1
SCHEMBL14018271 0.89 FFAR1 (0.48) NPSR1MAPTL3MBTL1FFAR1MEN1
SCHEMBL7597428 0.89 L3MBTL1 (0.51) NPSR1MAPTL3MBTL1FFAR1MEN1
SCHEMBL8749364 0.89 RAB9A (0.61) NPSR1MAPTL3MBTL1FFAR1MEN1
SCHEMBL11214221 0.89 FFAR1 (0.48) NPSR1MAPTL3MBTL1FFAR1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112174826-B Process for synthesizing nitro-diether by adopting narrow-distance parallel plate reactor 西安本清化学技术有限公司 2023-11-24 CN claimed
CN-115093327-A Synthesis process of oxyfluorfen intermediate nitro diether 宁夏一帆生物科技有限公司 2022-09-23 CN claimed
CN-108997127-B Production process for synthesizing 1, 3-di- (2-chloro-4-trifluoromethylphenoxy) -4-nitrobenzene 浙江禾本科技股份有限公司 2021-05-18 CN claimed
CN-112174826-A Process for synthesizing nitro diether by adopting narrow-distance parallel flat plate reactor 西安本清化学技术有限公司 2021-01-05 CN claimed
JP-60087257-A None JP disclosed
CN-119798088-A Preparation method and application of 4-nitro-1, 3-bis (2-chloro-4- (trifluoromethyl) phenoxy) benzene 首建科技有限公司 2025-04-11 CN disclosed
CN-112174826-B Process for synthesizing nitro-diether by adopting narrow-distance parallel plate reactor 西安本清化学技术有限公司 2023-11-24 CN disclosed
CN-112174826-B Process for synthesizing nitro-diether by adopting narrow-distance parallel plate reactor 西安本清化学技术有限公司 2023-11-24 CN disclosed
CN-115093327-A Synthesis process of oxyfluorfen intermediate nitro diether 宁夏一帆生物科技有限公司 2022-09-23 CN disclosed
CN-115093327-A Synthesis process of oxyfluorfen intermediate nitro diether 宁夏一帆生物科技有限公司 2022-09-23 CN disclosed
CN-113683511-A Synthesis method of 2-chloro-4-trifluoromethylphenyl-4 '-nitro-3' -ethoxy phenyl ether 广东立威化工有限公司 2021-11-23 CN disclosed
CN-108997127-B Production process for synthesizing 1, 3-di- (2-chloro-4-trifluoromethylphenoxy) -4-nitrobenzene 浙江禾本科技股份有限公司 2021-05-18 CN disclosed
US-4330324-A PREEMERGENCE APPLICATION ROHM AND HAAS COMPANY (US) 1982-05-18 US disclosed
US-4277624-A REPLACEMENT OF A NITRO GROUP WITH A HYDROXY, ETHER, MERCAPTAN, OR SULFIDE MITSUI TOATSU CHEMICALS, INC. (JP) 1981-07-07 US disclosed
US-4220468-A Herbicidal 4-trifluoromethyl-4-nitrodiphenyl ethers ROHM AND HAAS COMPANY (US) 1980-09-02 US disclosed
US-4185995-A Herbicidal 4-trifluoromethyl-4'nitrodiphenyl ethers ROHM AND HAAS COMPANY (US) 1980-01-29 US disclosed
US-4093446-A Herbicidal 4-trifluoromethyl-4-nitrodiphenyl ethers ROHM AND HAAS COMPANY (US) 1978-06-06 US disclosed
US-4063929-A Herbicidal 4-trifluoromethyl-4'nitrodiphenyl ethers ROHM AND HAAS COMPANY (US) 1977-12-20 US disclosed
US-4046798-A Herbicidal 4-trifluoromethyl-4'nitrodiphenyl ethers ROHM AND HAAS COMPANY (US) 1977-09-06 US disclosed
US-4017295-A 3'-ALKOXYETHOXYLATED 2-CHLORO-4-(CHLORO- OR TRIFLUOROMETHYL)-4'-NITRODIPHENYL ETHER ISHIHARA SANGYO KAISHA LTD. (JA) 1977-04-12 US disclosed