Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.47 |
| ▸ | PTGDR2 | Q9Y5Y4 | 5/20 | 0.45 |
| ▸ | PPARD | Q03181 | 3/20 | 0.40 |
| ▸ | PPARA | Q07869 | 3/20 | 0.40 |
| ▸ | KMO | O15229 | 4/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | BCR | P11274 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9820726 | 0.84 | ABCB11 (0.47) | ABCB11PTGDR2PPARDPPARAMGLL | |
| SCHEMBL10838777 | 0.84 | ABCB11 (0.47) | ABCB11PTGDR2PPARDPPARAMGLL | |
| SCHEMBL10881332 | 0.84 | PPARD (0.39) | PTGDR2PPARDPPARAPPARG | |
| SCHEMBL9359219 | 0.80 | KMT2A (0.44) | KMOTSHRHTR2AHTR2CHTR2B | |
| SCHEMBL9804348 | 0.78 | ABCB11 (0.43) | ABCB11PTGDR2PPARDPPARATSHR | |
| SCHEMBL9804459 | 0.78 | ABCB11 (0.43) | ABCB11PTGDR2PPARDPPARATSHR | |
| SCHEMBL9820875 | 0.77 | MAPK1 (0.44) | ABCB11PTGDR2TSHRHTR2AHTR2C | |
| SCHEMBL11013580 | 0.76 | TRPV1 (0.49) | ABCB11PTGDR2 | |
| SCHEMBL3369699 | 0.75 | PTGDR2 (0.43) | ABCB11PTGDR2MGLL | |
| SCHEMBL10387602 | 0.74 | KIF11 (0.40) | ABCB11PTGDR2PPARDPPARAIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0086746-A1 | Phenylamino-oxo-acetic acids and their esters as herbicidal antidotes for the protection of cultivated plants | CIBA-GEIGY AG (CH) | 1983-08-24 | — | — | EP | disclosed |