SCHEMBL11205489

SCHEMBL11205489

O=C(NCc1c(Cl)cccc1Cl)Nc1ccc(Oc2ccc(Cl)cc2)c(Cl)c1

nearest known ligand 0.64

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
GCGR P47871 1/20 0.64
PNLIP P16233 16/20 0.62
MAPT P10636 1/20 0.54
NPSR1 Q6W5P4 1/20 0.54
STK39 Q9UEW8 1/20 0.54
PARG Q86W56 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11008397 0.83 PNLIP (0.69) GCGRPNLIPMAPTNPSR1STK39
SCHEMBL10548838 0.82 CNR1 (0.66)
SCHEMBL10944935 0.81 GCGR (0.77) GCGRPNLIPMAPTNPSR1STK39
SCHEMBL11000732 0.81 EPHX1 (0.69) GCGRPNLIPMAPTNPSR1STK39
SCHEMBL22069619 0.77 PNLIP (0.64) GCGRPNLIPMAPTNPSR1STK39
SCHEMBL31536382 0.77 PNLIP (0.64) GCGRPNLIPMAPTNPSR1STK39
SCHEMBL10943518 0.77 GCGR (0.70) GCGRPNLIPMAPTNPSR1STK39
SCHEMBL7930411 0.76 PNLIP (0.63) GCGRPNLIPMAPTNPSR1STK39
SCHEMBL2171478 0.76 ESRRA (0.64) GCGRPNLIPMAPTNPSR1STK39
SCHEMBL10943317 0.76 GCGR (0.69) GCGRPNLIPMAPTNPSR1STK39

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0044410-B1 SUBSTITUTED N-BENZOYL-N'-PHENOXYPHENYL UREAS, PREPARATION THEREOF AND USE AS INSECTICIDES BASF Aktiengesellschaft (DE) 1983-12-21 EP claimed