Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 8/20 | 0.66 |
| ▸ | RAB9A | P51151 | 8/20 | 0.60 |
| ▸ | NPC1 | O15118 | 7/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | NAMPT | P43490 | 1/20 | 0.59 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.56 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.56 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.56 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.56 |
| ▸ | LSS | P48449 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11027327 | 0.87 | RAB9A (0.64) | CNR1RAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL11030224 | 0.87 | KMT2A (0.59) | CNR1RAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL9428324 | 0.86 | CNR1 (0.69) | CNR1RAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL11031455 | 0.84 | NPC1 (0.60) | CNR1RAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL5638898 | 0.84 | NAMPT (0.60) | SMN1; SMN2KMT2AMEN1POLBNAMPT | |
| SCHEMBL10545814 | 0.83 | TAS1R3 (0.61) | CNR1RAB9ASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL11051112 | 0.83 | RAB9A (0.60) | CNR1RAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL11205489 | 0.82 | GCGR (0.64) | — | |
| SCHEMBL8177097 | 0.80 | RAB9A (0.72) | CNR1RAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL11029084 | 0.80 | NPC1 (0.53) | CNR1RAB9ANPC1SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4833151-A | INTERFERES WITH METAMORPHOSES | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1989-05-23 | — | — | US | disclosed |
| US-4438110-A | 1-(MONO-SUBSTITUTED PHENYL)-3-BENZOYL UREA AND A PHOSPHOROUS CONTAINING COMPOUND | UNION CARBIDE CORPORATION (US) | 1984-03-20 | — | — | US | disclosed |