Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 6/20 | 0.46 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.42 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11205553 | 0.83 | PSMB8 (0.43) | CASRPSMB8PSMB5CA12CA1 | |
| SCHEMBL11206772 | 0.80 | PSMB8 (0.49) | CASRPSMB8PSMB5CA12CA1 | |
| SCHEMBL11195336 | 0.79 | PSMB8 (0.53) | CASRPSMB8PSMB5CA12CA1 | |
| SCHEMBL11204586 | 0.78 | PSMB8 (0.51) | CASRPSMB8PSMB5CA12CA1 | |
| SCHEMBL6014082 | 0.72 | PSMB8 (0.57) | CASRPSMB8PSMB5CA12CA1 | |
| SCHEMBL11188324 | 0.71 | TXN (0.45) | PSMB8PSMB5CA12CA1CA2 | |
| SCHEMBL2671314 | 0.69 | PSMB8 (0.53) | CASRPSMB8PSMB5CA12CA1 | |
| SCHEMBL12257976 | 0.68 | PSMB8 (0.64) | PSMB8PSMB5CA12CA1CA2 | |
| SCHEMBL31038102 | 0.68 | KMT2A (0.55) | CASRSMN1; SMN2LMNANPC1RAB9A | |
| SCHEMBL2128591 | 0.66 | PSMB8 (0.60) | PSMB8PSMB5CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0080861-A1 | Deodorized rubber additives | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1983-06-08 | — | — | EP | disclosed |