Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.65 |
| ▸ | HTR3A | P46098 | 2/20 | 0.45 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.45 |
| ▸ | KHK | P50053 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.41 |
| ▸ | FLT3 | P36888 | 2/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11200457 | 0.86 | HTR2C (0.61) | HTR2CGGPS1KHKHTR2AKDM4E | |
| SCHEMBL29648806 | 0.83 | HTR2C (0.57) | HTR2CHTR2AFLT3CDK2CDK6 | |
| SCHEMBL11201044 | 0.79 | HTR2C (0.70) | HTR2CHTR3AKDM4EALDH1A1HRH4 | |
| SCHEMBL11202691 | 0.77 | KHK (0.42) | HTR2CHTR3AKHKHTR2AKDM4E | |
| Hydrochloric Acid SCHEMBL11201994 | 0.76 | KHK (0.41) | HTR2CHTR3AKHKHTR2AKDM4E | |
| SCHEMBL11200114 | 0.75 | PRKCI (0.46) | HTR2CKHKHTR2AKDM4EALDH1A1 | |
| SCHEMBL11208313 | 0.74 | HTR2A (0.42) | HTR2CHTR3AKHKHTR2AKDM4E | |
| SCHEMBL11199721 | 0.74 | P2RY12 (0.50) | HTR2CKHKHTR2AKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL11197387 | 0.74 | PRKCI (0.45) | HTR2CKHKHTR2AKDM4EALDH1A1 | |
| SCHEMBL11198291 | 0.73 | GGPS1 (0.53) | HTR2CHTR3AGGPS1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0082023-A2 | Thienopyrimidine derivatives, their preparation and their medical use | SANKYO COMPANY LIMITED (JP) | 1983-06-22 | — | — | EP | claimed |
| EP-0082023-A2 | Thienopyrimidine derivatives, their preparation and their medical use | SANKYO COMPANY LIMITED (JP) | 1983-06-22 | — | — | EP | disclosed |