Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 5/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | APAF1 | O14727 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | UBE2N | P61088 | 1/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.43 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | HTR3A | P46098 | 2/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP4 | P49662 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11205604 | 0.79 | HTR2C (0.65) | HTR2CALDH1A1KDM4EHTR3AHRH4 | |
| SCHEMBL654362 | 0.77 | HTR2C (0.61) | HTR2CHRH1HRH4 | |
| SCHEMBL11200457 | 0.76 | HTR2C (0.61) | HTR2CALDH1A1KDM4EFLT3 | |
| SCHEMBL11201872 | 0.75 | GAA (0.53) | HTR2CALDH1A1HPGDKDM4EMAPT | |
| SCHEMBL11197408 | 0.74 | KDM4E (0.52) | HTR2CALDH1A1HPGDKDM4EAPAF1 | |
| Hydrochloric Acid SCHEMBL11206153 | 0.73 | KDM4E (0.51) | HTR2CALDH1A1HPGDKDM4EAPAF1 | |
| SCHEMBL29648806 | 0.73 | HTR2C (0.57) | HTR2CFLT3 | |
| SCHEMBL11817813 | 0.73 | ALDH1A1 (0.70) | ALDH1A1HPGDKDM4EAPAF1POLB | |
| SCHEMBL30575992 | 0.73 | ALDH1A1 (0.70) | ALDH1A1HPGDKDM4EAPAF1POLB | |
| SCHEMBL793832 | 0.73 | HTR2C (0.57) | HTR2CALDH1A1HPGDKDM4EHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0082023-A2 | Thienopyrimidine derivatives, their preparation and their medical use | SANKYO COMPANY LIMITED (JP) | 1983-06-22 | — | — | EP | claimed |
| EP-0082023-A2 | Thienopyrimidine derivatives, their preparation and their medical use | SANKYO COMPANY LIMITED (JP) | 1983-06-22 | — | — | EP | disclosed |