Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | KHK | P50053 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP4 | P49662 | 1/20 | 0.38 |
| ▸ | CASP5 | P51878 | 1/20 | 0.38 |
| ▸ | PLK4 | O00444 | 1/20 | 0.37 |
| ▸ | PAK4 | O96013 | 1/20 | 0.37 |
| ▸ | HTR3A | P46098 | 2/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | PRKCI | P41743 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | APAF1 | O14727 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11202691 | 0.84 | KHK (0.42) | HTR2AKDM4EALDH1A1HTR2CKHK | |
| Hydrochloric Acid SCHEMBL11201994 | 0.82 | KHK (0.41) | HTR2AKDM4EALDH1A1HTR2CKHK | |
| SCHEMBL11200730 | 0.82 | KDM4E (0.49) | HTR2AKDM4EALDH1A1HTR2CCASP1 | |
| SCHEMBL11199721 | 0.81 | P2RY12 (0.50) | HTR2AKDM4EALDH1A1HTR2CKHK | |
| SCHEMBL11204604 | 0.79 | P2RY12 (0.42) | HTR2AKDM4EALDH1A1HTR2CKHK | |
| SCHEMBL11200417 | 0.77 | MEN1 (0.45) | KDM4EALDH1A1TSHRSMN1; SMN2MAPT | |
| SCHEMBL11201826 | 0.77 | CETP (0.42) | HTR2AKDM4EALDH1A1HTR2CKHK | |
| SCHEMBL11205604 | 0.74 | HTR2C (0.65) | HTR2AKDM4EALDH1A1HTR2CKHK | |
| SCHEMBL11200202 | 0.74 | KHK (0.38) | HTR2AKDM4EALDH1A1HTR2CKHK | |
| SCHEMBL11206366 | 0.73 | HTR2A (0.39) | HTR2AKDM4EALDH1A1HTR2CKHK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0082023-A2 | Thienopyrimidine derivatives, their preparation and their medical use | SANKYO COMPANY LIMITED (JP) | 1983-06-22 | — | — | EP | disclosed |