Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PRKCI | P41743 | 2/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP4 | P49662 | 1/20 | 0.33 |
| ▸ | CASP5 | P51878 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11202792 | 0.88 | KHK (0.38) | KDM4EALDH1A1PRKCIHRH1SMN1; SMN2 | |
| SCHEMBL11203905 | 0.84 | PRKCI (0.35) | KDM4EALDH1A1PRKCISMN1; SMN2MAPT | |
| SCHEMBL11201865 | 0.82 | ALDH1A1 (0.39) | KDM4EALDH1A1PRKCIHRH1SMN1; SMN2 | |
| Maleic Acid SCHEMBL11207421 | 0.82 | P2RY12 (0.35) | KDM4EALDH1A1SMN1; SMN2HTR2AMAPT | |
| Fumaric Acid SCHEMBL11207423 | 0.82 | P2RY12 (0.35) | KDM4EALDH1A1SMN1; SMN2HTR2AMAPT | |
| SCHEMBL11203967 | 0.80 | KDM4E (0.38) | KDM4EALDH1A1HRH1SMN1; SMN2USP2 | |
| SCHEMBL11197431 | 0.78 | HRH1 (0.40) | KDM4EALDH1A1PRKCIHRH1SMN1; SMN2 | |
| SCHEMBL11199815 | 0.78 | PDE4A (0.43) | PRKCIHRH1SMN1; SMN2USP2TDP1 | |
| SCHEMBL11203991 | 0.76 | HTR2A (0.38) | KDM4EALDH1A1HRH1SMN1; SMN2USP2 | |
| SCHEMBL11205725 | 0.75 | PRKCI (0.46) | KDM4EALDH1A1PRKCIHRH1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0082023-A2 | Thienopyrimidine derivatives, their preparation and their medical use | SANKYO COMPANY LIMITED (JP) | 1983-06-22 | — | — | EP | disclosed |